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Top asked Pharma Interview Questions for Freshers (New updated)

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Getting a job in the pharmaceutical field is a dream for all pharmacy students, especially freshers. At that time, Most of us will have to go through a formal interview with an interviewer. Before writing this post I faced more than 100 interviews with different pharmaceutical industries. Based on this we have prepared Pharma Interview Questions And Answers For Freshers for QA, QC, MR, and Pharmacists. For most people, the interview is the most difficult part since they are always concerned about what questions will be asked and how they should reply.

Pharma Interview Questions for Freshers

The way applicants respond to Pharma job interview questions will have a big influence on whether or not they receive the job. Applicants should be confident in their responses and present professionalism during the interview, as well as answer interview questions honestly and respectfully. This is not to imply that some personalities should not be projected, but it should be consistent with the interviewers. Some of the Pharma Interview Questions for Fresher candidates are explained below.

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Department Wise Common Pharma Interview Questions for Freshers

These questions are very important, these types of questions are generally asked and filled in during the first assessment form.

Q. Tell me about yourself
Ans: Start with something like that, My name is Sanjay, and I am a pharma graduate, I completed my Degree from (college name) in a (year). My father is a farmer and my mother is a Housewife.

Q. What do you know about our company?
Ans: Tell them about the company’s history, direction, progress, culture, and products.

Q. Tell me about your strength.
Ans: Tell them about your strength so that they can answer like Supportive, or Diplomatic. Good communication, Pressure handling, truthfulness, creativity, organization, willpower, dedication, and motivation.

Q. What is your weakness?
Ans: You can tell them about your weaknesses like if you have in following:

  • I sometimes lack overconfident
  • I have trouble asking for help
  • I focused too much on details so it consumed lots of time.

Q. Why should we hire you?
Ans:

  • I can do the work and deliver good results within the time framework
  • I can manage a team or work as a team to grow more
  • I have skills like soft skills, and technical skills, perform multiple tasks at once
  • Education and training deliver

Q. Are you a hard worker or a smart worker?
Ans: Sir, basically I am a hard worker, but now I can complete the project by doing hard work within the time frame.

Q. What are your salary expectations?
Ans: As a fresher, I expect the salary as per company norms or policy

Pharma Interview Questions Production for fresher

Q. Why do you want to join Production?
Ans: As I am capable of working in any environment, I can handle pressure. I am also interested in manufacturing activities.

Q. What are the different types of tablets in pharma?
Ans:

  • Coated tablets
  • Uncoated tablets
  • Effervescence tablets
  • Long release tablets
  • Modified-release tablets
  • Sugar-coated tablets
  • Enteric-coated tablets
  • Dispersible tablets

Q: What is the Granulation?
Granulation is the size enlargement process during which small particles combine to form a large mass. It’s also called agglomeration.

Q: What is the coating equipment which is being used?
Ans: For the coating process mainly following 3 types of equipment are used:
✓ Conventional coating pan
✓ Perforated Coating pan
✓ Fluidized bed coater

Q: What is the leak test of packaging?
Ans: The test that is used to check the integrity of packed strips, blisters, bottles, and small sachets containing tablets, capsules, and dry powders is called the leak test. leak test apparatus is used to test the quality of the packing process and to check the proper sealing of the enclosed product inside the cavity. A methylene blue color is applied to detect leakage in blisters or stripes, and the solution in the desiccators must be changed daily or as needed.

Q. What is the Leak test in Packing?
Ans. The term “leak test” refers to the procedure used to examine the integrity of packed strips, blisters, bottles, and small sachets holding tablets, capsules, and dry powders. Leak test Equipment is used to assess the effectiveness of the packing process and ensure that the product’s seals are completely intact and that no water should enter the pack. It is made to detect even small punctures and defects in products that have been packed.

Q. What are the units of Hardness in tablets?
Ans.Kilogram (kg), Newton (N), Pound (lb), Kilopond (kp) and Strong-Cobb (SC), Kilo force (Kgf)

Q. What is GMP stand for?
Ans: GMP Stands for good manufacturing practices.

Q. Who is cGMP?
Ans: Current good manufacturing practices.

Q. What are capsules in dosage form?
Ans: The capsule may be in granules, powder, and semi-solid form.

Q. Describe the types of capsules.
Ans: Capsules are of two types: Hard gelatin capsules and soft gelatin capsules.

Q. What is packing in pharmaceuticals and their types?
Ans: Packing is the enclosed envelopes of the medicament in the form of strips, blisters, and bottles.

Q. Types of packing in pharmaceuticals?
Ans: There are basically three types of packaging in pharma

  • Primary packing
  • Secondary packing
  • Tertiary packing

Q. What is Primary Packing?
Ans: Primary packing mainly involves enclosing the medication inside the pocket or cavity to prevent the medicine from external environments.

Q. What is secondary Packing?
Ans: Secondary packing is used for aggregation purposes either by packing in cartons or slives to get good distribution practice.

Q. What is tertiary packing?
Ans: Tertiary packing is mainly packing the bundles of medicine in corrugated boxes to prevent the drugs from damage during transport, and also from external or physical damage.

Q. What is the difference between disintegration and dissolution?
Ans: Disintegration is the process by which an oral dose form breaks down into smaller aggregates. (The ‘break-up time of a solid dosage form is called disintegration time.)

Dissolution, on the other hand, is the process by which a solid substance dissolves in a solvent to produce a solution. The affinity between the solid substance and the liquid is what controls it.

Q. What is room temperature?
Ans: The room temperature is 25°C

QC Pharma Interview Questions for Freshers

Q: What is the IR spectroscopy and Range of IR
Ans: Infrared spectroscopy is used to identify functional groups, measure the impurity in the sample, and detect impurities. Its ranges are 14000 to 4000 cm-1

Q: What is the range of UV-Vis spectroscopy and its Ranges?
Ans: It is used to measure the concentration and impurity in the sample. Its range Ranges from 200 to 800 nm.

Q: What is the use of NMC spectroscopy and its Range?
Ans: NMC is used to identify the structure of the molecules in the sample and their purity. NMC spectroscopy range ranges from 0 to 1000 MHz.

Q: What is the use of X-ray spectroscopy and its Ranges?
Ans: It is used to identify the crystal structure of the molecules, measure the impurity of the sample, and detect impurities. Its range Ranges from 0.1 to 10 nm.

Q: What is the use of mass to charge ratio?
Ans: mass to charge ratio is used in mass spectroscopy which is an analytical technique that measures the mass and abundance of the ions in the sample.

Q: What is the IR spectroscopy and Range of IR
Ans: Infrared spectroscopy is used to identify functional groups, measure the impurity in the sample, and detect impurities. Its ranges are 14000 to 4000 cm-1

Q: What is the range of UV-Vis spectroscopy and its Ranges?
Ans: It is used to measure the concentration and impurity in the sample. Its range Ranges from 200 to 800 nm.

Q: What is the use of NMC spectroscopy and its Range?
Ans: NMC is used to identify the structure of the molecules in the sample and their purity. NMC spectroscopy range ranges from 0 to 1000 MHz.

Q: What is the use of X-ray spectroscopy and its Ranges?
Ans: It is used to identify the crystal structure of the molecules measure the impurity of the sample and detect impurities. Its range Ranges from 0.1 to 10 nm.

Q: What is the use of mass to charge ratio?
Ans: mass to charge ratio is used in mass spectroscopy which is an analytical technique that measures the mass and abundance of the ions in the sample.

Q: What are the steps of quality control in the pharmaceutical industry?
Ans: Quality control is a critical process in the pharmaceutical industry to ensure that drugs are safe, effective, and of high quality. The following are the typical steps of quality control in the pharmaceutical industry:
Sampling and testing: The first step in quality control is to take representative samples of the drug product and test them for various quality attributes, such as potency, purity, and stability.
Analytical method development: In order to accurately test the drug product, a suitable analytical method must be developed that can detect and quantify the active ingredient and any impurities.
Stability testing: Pharmaceutical products must be tested for stability over time to ensure that they retain their quality and efficacy throughout their shelf life.
Documentation: All quality control activities must be documented thoroughly, including the sampling and testing procedures, analytical method development and validation, and stability testing results.
Release testing: Before a drug product can be released for sale or distribution, it must undergo rigorous testing to ensure that it meets all quality standards and specifications.
Continuous monitoring: Quality control is an ongoing process that continues throughout the life cycle of the drug product. Manufacturers must monitor product quality and make any necessary adjustments to maintain consistent quality.
Auditing and inspections: Regulatory authorities may conduct audits and inspections of pharmaceutical manufacturing facilities to ensure that they comply with all applicable quality standards and regulations.

Q: What are the different techniques included in Qualitative analysis?
Ans: Qualitative analysis includes various techniques such as:
Chromatography: It is a separation technique that separates the components of a mixture based on their chemical properties. High-performance liquid chromatography (HPLC) and gas chromatography (GC) are commonly used in pharmaceutical analysis.
Spectroscopy: It is a technique that uses electromagnetic radiation to measure the interaction of a sample with light. Some of the commonly used spectroscopy techniques in pharmaceutical analysis are infrared (IR), ultraviolet-visible (UV-Vis), nuclear magnetic resonance (NMR) spectroscopy., Raman Spectroscopy, and X-ray spectroscopy.
Mass Spectrometry: It is an analytical technique that ionizes a molecule and separates the ions based on their mass-to-charge ratio. Mass spectrometry (MS) is used to determine the molecular weight of a drug or its related substances.
Thermal Analysis: It is a technique that studies the physical and chemical properties of a substance as a function of temperature. Differential scanning calorimetry (DSC) and thermogravimetric analysis (TGA) are commonly used thermal analysis techniques in pharmaceutical analysis.
Microscopy: It is a technique that uses a microscope to study the structure and morphology of a substance. Polarized light microscopy (PLM) and scanning electron microscopy (SEM) are commonly used in pharmaceutical analysis.

Q: What techniques are used in Quantitative analysis?
Ans: Quantitative analysis techniques are mainly used to quantify any compound or substance in the sample. These techniques are based in:
✓ The quantitative performance of suitable chemical reaction and either measuring the amount of reagent added to complete the reaction or measuring the amount of reaction product obtained,
✓ The characteristic movement of a substance through a defined medium under controlled conditions,
✓ Electrical measurement,
✓ Measurement of some spectroscopic properties of the compound.

Q: What is the main difference between qualitative and quantitative analysis?
Ans: Qualitative analysis involves the identification of the compound or chemical based on its chemical (absorption, emission) or physical properties like Melting point, and boiling point).
Quantitative analysis refers to the estimation or determination of conc. or amount of the chemical compounds or components.

Q: What is the Friability Test of a Tablet?
Ans: Friability is defined as the %age of weight loss of powder from the core surface of the tablets due to mechanical or physical action and the test is performed to measure the weight loss during transportation.
Friability (%) =W1— W2/W1X100 Where, W1 = Weight of Tablets (Initial / Before Tumbling) &
W2 = Weight of Tablets (After Tumbling or friability)
Limit: Friability (%) = Not More Than 1.0 %

Q: Can you explain HPLC?
Ans: HPLC stands for High-performance liquid chromatography. It is a widely used analytical technique in the pharmaceutical industry for quality control of drugs and their related substances. It is a powerful tool for the separation, identification, and quantification of drug molecules and their impurities.
In pharmaceutical quality control, HPLC is used to:
✓ Identify and quantity the active pharmaceutical ingredient (All) in a drug product.
✓ Determine the impurity profile of a drug substance or drug product.
✓ Analyse the stability of a drug substance or drug product under different conditions.
✓ Test the dissolution profile of a drug product.
✓ Monitor the Process of drug development and manufacturing.

Q: Can you explain DSC?
Ans: DSC stands for Differential Scanning Calorimetry. DSC is a technique that measures the difference in heat flow between a sample and a reference material as they are heated or cooled. In pharmaceutical analysis, DSC is often used to study the physical and chemical changes that occur in drug substances and formulations during heating or cooling, such as melting, recrystallization, and degradation.

Q: Can you explain TGA?
Ans: TGA stands for Thermogravimetric Analysis. TGA is a technique that measures the change in weight of a sample as it is heated or cooled in a controlled atmosphere. TGA can provide information on the thermal stability and decomposition behavior of a sample. In
pharmaceutical analysis, TGA is often used to study the thermal stability of drug substances and formulations, as well as the purity of the sample. TGA can also be used to determine the moisture content of a sample by measuring the weight loss due to the evaporation of water.

Q: Can you explain PLM?
Ans: PLM stands for Polarized Light Microscopy. PLM is a technique that uses polarized light to examine the optical properties of materials. PLM can be used to examine the microstructure of materials, such as crystalline structures and fiber orientation. In pharmaceutical analysis, PLM is often used to examine the physical properties of drug substances and formulations, such as the crystal form, particle size, and shape.

Q: Can you explain SEM?
Ans: SEM stands for Scanning Electron Microscopy. SEM is a technique that uses a focused beam of electrons to examine the surface of a material. SEM can provide detailed information on the morphology, size, and composition of materials at a micro- and nanoscale level. In pharmaceutical analysis, SEM is often used to examine the surface morphology of drug particles, such as the size and shape of particles, and to investigate the distribution of active pharmaceutical ingredients in a formulation.

Q: What is pH? What is the formula for pH?
Ans: pH stands for Potential of Hydrogen. pH is a measure of how acidic or basic a chemical solution is. The pH scale runs from 0 to 14—a value of seven is considered neutral, less than 07 is acidic and greater than 07 is basic.
pH = -loglO[H+][H+] = 10-pH
pH is the negative base 10 logarithms (“log” on a calculator) of the hydrogen ion concentration of a solution.

Q: What is Beer-Lambert’s Law?
Ans: Beer-Lambert’s Law, also known as the Beer-Lambert-Bouguer Law, is a fundamental principle in spectroscopy. It is used to determine the concentration of drug molecules in a sample. Mathematically, Beer-Lambert’s Law is expressed as A = Ecl
Where: A = Absorbance, E = Molar absorptivity (also known as the extinction coefficient),c = Concentration of the sample, I = Path length of light through the sample
According to Beer-Lambert’s Law, the absorbance of a sample increases linearly with the concentration of the sample and the path length of light through the sample. The molar absorptivity is a constant for a given compound and is dependent on the wavelength of light used.

QA Pharmaceutical Interview Questions for Freshers

Here are the most important pharma questions that have been asked before in some big MNCs like; Sun Pharma, Torrent, Cipla, and Alkem Pharma.

Q. What is QA in a pharma interview?
Ans: QA stands for Quality assurance, The QA department is responsible for ensuring the quality of products through their lift periods, sampling intermediate and final products, and reviewing or assurance documents related to the products. complying with the non-confirmation reports, market recalls, and market problems.

Q. What is ADL in pharma?
Ans: ADL stands for Analytical Development Department, As in the ADL department, you have to develop the methods used in the QC department, and as per the QC department, you have to just follow the set methods. So as per learning objectives, the ADL unit is the best way to start up and after getting 1 or 2 years of experience in method development you can switch either to QC or QA.

Q. What is BMR in pharma?
Ans: BMR is the Batch Manufacturing records to record the processing activity.

Q. What is calibration in pharma?
Ans: Calibration is the accurate measurement of any instrument or analytical instrument.

Q. What are analytical R and D?
Ans: R&D stands for Research and Development

Q. What is an API plant?
Ans: The API plant is engaged in manufacturing Active Pharmaceutical Ingredients.

Q. What is the master formula?
Ans: Master formulas act as evidence for the manufacturing process. it is a master document containing the all manufacturing processes for products. the master formula is prepared by the R&D department of the organization.

Q. Which is Phase 3 of process validation?
Ans:

  • Process design
  • Process validation
  • Continue process validation

Q. What are OOS and OOT in pharma?
Ans: OSS is out of specification: if the testing result of the sample found outside of comparison limits is called OOS

OOT is out of trend: if the comparison of historical data with respect to time.

Q. What is cleaning validation in pharma?
Ans: Since agency documents like the Inspection Guide for Bulk Pharmaceutical Chemicals and the Biotechnology Inspection Guide briefly touched on this topic, validation of cleaning techniques has been the subject of substantial controversy. These Agency materials make it crystal clear that techniques (processes) for cleaning should be confirmed.

Q. What is line clearance?
Ans: it is the verification process by the products and QA person to protect the products against undesirable effects or it is a standard operating process to ensure the work area, equipment, and environments are free from the last manufactured products.

Q. What are batch packing Records (BPR) in Pharma?
Ans: The batch packing record, which details the technique and step-by-step instructions to be followed throughout the packing of each batch, is a written record of the batch from the dispensing to the shipment stage. It comprises accurate packing data and functions as confirmation that batches were correctly created, examined by production, and validated by quality assurance staff. It also includes information such as who performed the activity, when the activity was performed, etc.

Q. Why C is small in cGMP?
Ans: Small c is used for current in GMP.

Final Thought

You must always be properly prepared for the interview, whether it is your first job after college or a well-considered career shift. Check to see if your resume is well-written. A professionally prepared resume is a sensible investment if you want to stand out from the crowd. You will be called for a job interview if you have a well-written CV and cover letter. Many people are intimidated by the interview process, but it should be viewed as a discussion to evaluate if you are qualified for the job and if this organization is a good fit for you. Remember that preparation for an interview is just as crucial as the interview itself.

PFD on Pharma Interview Questions for Freshers:

3 thoughts on “Top asked Pharma Interview Questions for Freshers (New updated)”

  1. During the interview, they asked for our semester marks and credit marks, which are essential for freshers looking to work in the pharmaceutical industry. Securing a job in the pharmaceutical industry is my passion. However, I am feeling quite fearful about my semester marks and credit marks.

    Reply

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