500+ MCQs on Pharmacology (Most important) in 2024

MCQs on Pharmacology play a crucial role in improving performance across various exams such as those for pharmacists, nurses, GPAT, and related fields. This section comprises only 250 questions; additional questions will be featured in the subsequent part on Pharmacology Multiple Choice Questions for pharmacy students.

Scope of pharmacology MCQs:

The scope includes general preparation and identifying the types of questions asked every year in competitive exams. General questions on Pharmacology MCQs (BP404T) help understand your preparation level and potential marks achievable. MCQs on pharmacology PDF or notes will be provided here. If needed, please comment below.

Section Wise MCQs on Pharmacology:

Introduction to pharmacology MCQs, please let us know which section from these are you willing to learn so that it will be covered by us.

1. Route of Drug Administration
2. Bioavailability
3. Plasma Protein Binding
4. Pharmacovigilance
5. Microsomal enzyme and Enzyme Induction
6. First, pass the metabolism
7. Kinetics of Elimination
8. Loading dose and Maintenance dose
9. G protein-coupled receptors
10. Therapeutic index
11. Factors modifying drug actions
12. Placebo, Rational prescribing
13. Tolerance
14. Teratogenicity

List of 500 MCQs on Pharmacology Questions and Answers

Q: The diagnostic agent used in Myasthenia gravis is
Pralidoxime
Neostigmine
Physostigmine
Edrophonium

Q: How many amino acids are present in chains A and Chain B of insulin?
20 and 30
20 and 31
21 and 30
21 and 31

Q: Neostigmine bromide is used orally for the treatment for
Glaucoma
parkinsonism
Myasthenia gravis
All of above

Q: Anti-TB drugs that can cause ototoxicity is
Streptomycin
Rifampicin
Ethambutol
Pyrazinamide

Q: In Rheumatic arthritis use the following agents
Silver
Gold
Copper
Antimony

Q: The following antidote is used in cyanide poisoning
Potassium nitrite
Sodium thiosulphate
Sodium bicarbonate
sodium chloride

Q: The antiviral agent is also used in the treatment of Parkinsonism
Levodopa
Amantadine
Selegiline
Carbidopa

Q: Cyclopropane is a …
Local anesthetic
General anesthetic
Anti-oxidant
Antibiotic

Q: Indomethacin is used for the treatment of
Rheumatoid arthritis
Gout
Ankylosing spondylitis
All of above

Q: A centrally-acting muscle relaxant is
Baclofen
Chlormezanone
Diazepam
All of above

Q: The use of tetracycline during pregnancy is avoided due to
It is teratogenic
It affects the bone growth of the fetus
It can cause abortion
It can affect the growth of the limb

Q: Allopurinol is used in the treatment of
Rickets
Gout
Osteomalacia
None of these

Q: Mini pill contains:
Estrogen
Non-Hormonal contents
Progesterone
Estrogen and Progesterone

Q: Longer use of organic nitrates in angina Pectoris causes one of the following side effects:
Hepatotoxicity
Tolerance
Aplastic anemia
Nephrotoxicity

Q: A potent 5HT receptor agonist used in migraine is:
Clonidine
Stemetil
Sumatriptan
Propranolol

Q: The drug of choice for diarrhea is
Metoclopramide
Cefixime
Levofloxacin
Loperamide

Q: Anaphylaxis reaction is due to which antibody:
IgA
IgE
IgM
IgG

Q: A synthetic opioid drug for severe pain is
Ibuprofen
Analgin
Buprenorphine
Diclofenac

Q: A drug used in the treatment of parkinsonism is:
Carbimazole
Carbidopa
carbachol
Carbamazepine

Q: The term analgesic means:
Pain-killer
ANti-Fungal
Anti-diabetic
Antibiotic

Q: A new anticonvulsant with a structural analog of GABA is
Phenytoin
Primidone
Gabapentin
None of these

Pharmacy MCQs | Pharma MCQ Book pdf

Q: Trihexyphenidyl is used in:
Parkinsonism
Mania
Epilepsy
Diarrhea

Q: Cinnarizine is a…
Antihistaminic
Sedative
Anticholinergic
All of above

Q: Zafirlukast is used as an anti-asthmatic act:
Prostaglandin antagonist
Lipoxygenase inhibitor
Cyclooxygenase inhibitor
Leukotriene receptor antagonist

Q: Piracetam is used to improve the function of:
Brain
Eye
Ear
None of above

Q: Type-I hypersensitivity example:
Complement-mediated cell damage
IgE mediated reactions
serum Sickness
cell-mediated immunity reaction

Q: Imipramine is used as:
Tranquilizer
Anti-convulsant
Anti-depressant
Analeptic

Q: Colchicine is used mainly to treat:
Diabetes
Cancer
Rheumatoid arthritis
Acute gout

Q: The chemical name (IUPAC name) of chloroquine is:
7-chloro-4-(4-diethylamino-1-methyl butyl amino)-quinoline
N-(2-chloroquine)-2 methyl pentane amine
2-Chloro methane 3-quinine
3-Chloro fluoro-4.5 ethanamine

Q: In Diabetic keto-acidosis given
Regular (crystalline zinc) insulin
Crystalline insulin
Zinc insulin
Regular insulin
Find: Answer

Q: Oxytocin is used to:
Induce labor
Raise B.P
Prevent conception
None of above

Q: Antidote for heparin overdose is:
B.AL
Atropine
Protamine sulphate
Dicumarol

Q: Opium is used as:
Sedative
stimulant
Narcotic analgesic
Diaphoretic

Q: Nitrofurantoin is mainly used to treat:
Syphilis
UTI
RTI
None of above

Q: Tetraogenic drug causes toxicity to:
Liver
Kidney
Fetus
Brain

Q: The major organ responsible for drug detoxification:
Lung
Liver
Muscular tissue
Intestine

Q: One of the following is not a parasympathetic response:
Contractile intestinal smooth muscle
Increase heart rate
Decrease heart rate
Stimulates gastric secretion

Q: Generally, steroid hormones are administered in the form of
Dental cones
Multilayered tablets
Soluble tablets
Implants

Q: Anti-inflammatory drugs used in rheumatoid arthritis is
Lithium carbonate
sodium antimony gluconate
sodium aurothiomalatete
Potassium perchlorate

Q: Aluminium hydroxide gel is used as
Flavoring agents
Carminative
antacids
Sedatives

Q: Physical property which affects drug absorption:
Surface tension
Flow
Density
solubility

Q: The drugs used both as antacids and laxatives is
Magnesium sulphate
sodium salphate
Magnesium hydroxide (Milk of magnesia)
Magnesium chloride

Q: Cis-platinum is used as
Antioxidants
Antiseptic
Antineoplastic agent
None of above

Q: Hyperlipidemia is an excess of
Cholesterol and triglyceride
Free fatty acid
Glycerol
ketone bodies

Cardiovascular MCQs on Pharmacology

Q: The following are cardio-selective beta-adrenergic blocking agents except
Labetalol
Acebutolol
Atenolol
Metoprolol

Q: Mala-N contains?
Non-ethisterone
Ethynyl oestradiol
Both A and B
NOn of above

Q: The hypothalamic function includes all except
Regulation of posterior pituitary
Regulation of anterior pituitary
Control of reproduction
Control of respiration

Q: Both alpha and beta blockers used in hypertension is
Labetalol
metoprolol
Acebutolol
Pindolol

Q: The parathyroid gland regulates the absorption of calcium. which of the following is used in hypoparathyroidism
estrogen
levothyroxine
prednisolone
dihydrotachysterol

Q: Isoprenaline is usually administrated by
I.V
I.M
Sublingual
Inhalation

Q: Metabolite of spirolactone is
amrinone
milrinone
canrinone
samzonone

Q: Disulfiram (Antabuse) is used to treat
alcoholism
diabetes
mumps
gout

Related MCQs: Pharmaceutics MCQs

Pharmacology MCQ Book pdf | Pharmacology MCQs with Answers pdf

Q: Sulfonamides are metabolized by humans principally by
acetylation
deamination
oxidation
conjugation

Q: which is the major side effect of sulfonamide
crystalluria
peripheral neuritis
kernicterus
all of the above

Q: which are the following metabolites of hydroxyzine
astemizole
cetirizine
loratadine
terfenadine

Q: Vit K is associated with
Pellagra
Blood clotting
Bones
Haemoglobin

Q: Which of the following inhibits ketoconazole absorption
Ranitidine
Nizatidine
cimetidine
Famotidine

Q: Which of the following sulfinamide after metabolism is converted into sulfapyridine and 5-amino salicylic acid
Sulfamethoxazole
Sulfacetamide
Sulfadiazine
Sulfasalazine

Q: The ideal antiseptic concentration of ethyl alcohol is:
50%
75%
70%
95%

Q: Paracetamol overdose is treated with
N-acetyl cysteine
Calcium disodium EDTA
d- penicillamine
Dimercaprol

Q: Nicotinic acid is used to prevent
Blood clotting
Pellagra
Bones
Haemoglobin

Q: The drug used as an anticonvulsant is
Cocaine
Primidone
Amethocaine
Nikethamide

Q: The antineoplastic drug containing pyrimidine nucleus
Busulfan
Cisplatin
Mitomycin
Fluorouracil

Q: The anti-cytotoxic drug is
Idoxuridine
Levodopa
Acetazolamide
S-Fluorouracil

Q: The drug used in respiratory depression is
Metamizole
Metronidazole
Leptazole
All of above

Q: The anti-arrhythmic drug is
Paraquine
Procainamide
Pilocarpine
Atropine

Q: The general anesthetic administered I.V is
Phenobarbitone
Ketamine
Allobarbitol
Picrotoxin

Q: The drug of choice for the treatment of typhoid fever is
Erythromycin
Amoxicillin
Chloramphenicol
Nafcillin

Q: Gabapentin is an example of
Expectorant
Anti-convulsant
Analeptic
Hallucinogens

Q: Sulphaguanidine is used as an
Antidiarrhoeal
Anti-malarial
Antitussive
Anti-coagulant

Q: Liver extracts are used as
Anti-coagulant
Coagulant
Haematinic
Atherosclerosis

Q: Angioedema is an adverse drug reaction affecting the
Pancreas
Skin
Liver
Gastrointestinal tract

Q: Anaphylactic allergy falls under which of the following types of hypersensitivity
Type I
Type II
Type III
Type IV

Q: Is propyl thiouracil similar to one of the following drugs in pharmacological action?
Azathioprine
Chlorambucil
Methimazole
Acyclovir

Q: Which of the following drugs is similar to acarbose in classification
Toibutamine
Glipizide
Miglitol
Pioglitazone

Q: Wheal and flare reaction is a characteristic reaction associated with the identification of
Type I hypersensitivity reaction
Type II hypersensitivity reaction
Type III hypersensitivity reaction
Type IV hypersensitivity reaction

Lippincott Pharmacology MCQ

Q: Which of the following is a pure opioid antagonist?
Butorphanol
Nalbuphine
Buprenorphine
Naloxone

Q: Which of the following drugs causes maximum dependence?
Diethylmorphine
Diacetylmorphine
Dimethyl morphine
Diphenoxylate

Q: Centrally acting muscle relaxant
Halothane
2- Tubocurarine
Mephenesin
Succinylcholine

Q: Latanoprost has one of the following mechanisms of action in glaucoma
Miosis
Prostaglandin analogs
Carbonic anhydrase inhibitor
Decrease the formation of aqueous humor

Q: Which one of the following is used as an osmotic purgative?
Senna
Milk of magnesia
Extract of rhubarb
Aluminium hydroxide gel

Q: Promethazine Hcl is used in
Motion sickness
Glaucoma
Parkinsonism
Amoebiasis

Q: Phenylpropanolamine is used as
Nasal decongestant
Anti-coagulant
Antitussive
Anti-viral

Q: A potent H2 receptor antagonist which is
aluminium hydroxide
Ranitidine
Omeprazole
Mesalazine

Q: The antisecretory drug used in peptic ulcers is
Calcium carbonate
Sulphasalazine
Magnesium oxide
Milk of magnesia

Q: Magaldrate produces a sustained effect in
Peptic ulcer
Diarrhea
Dysentery
Amoebiasis

Q: The following is a selective α2 adrenoceptor antagonist:
Prazosin
Yohimbine
Phentolamine
Clonidine

Q: Phenytoin sodium (Dilantin) is used as an
ANtihypertensive agent
Antiulcer drug
Antimalarial
Anticonvulsant

Q: The anti-inflammatory drug used as antirheumatic is
Busulphan
Ibuprofen
imipramine
crocin

Q: Amitriptyline is used in
Epilepsy
mania
Severe depression
Severe depression

Q: The drug used in the treatment of amoebiasis is a
Paracetamol
Lasix
Di-iodoquin
physostigmine

Q: The primary indication of tamoxifen citrate is:
Female infertility
Endometrial carcinomaa
Breast carcinoma
Endometriosis

Q: Azithromycin is mainly eliminated by route…
Hepatic
Renal
Perspiration
Semen

Q: A specific benzodiazepine antagonist used for the treatment of diazepam overdosing (Poisoning)
Meprobamate
Flumazenil
Hydroxyzine
Buspirone

Q: What is the nature of heparin?
Acidic
Basic
Amphoteric
None of above

Q: Which one of the following is the mechanism of ranitidine?
Prostaglandin release
Stimulated gastrin release
Stimulated histamine release
Inhibit gastric acid secretion

Q: Which the following is a side effect of cimetidine
Diarrhea
Constipation
Inhibit hepatic enzyme
None of above

Q: Which of the following release cytolytic T4 proliferating cells that are used in cancer
IL1
IL6
IL8
IL2

Q: Diabetes mellitus Mellitus is characterized by
Hypoglycemia
Hyperglycemia
Hypocalcemia
Dehydration

Q: Maximum absorption of the drug in the gastrointestinal tract is achieved by facilitated diffusion
Active diffusion
Facilitated diffusion
Active transport
passive diffusion

Q: Which of the following drugs is an MAO-B inhibitor?
Selegiline
Dopamine
Adrenaline
isoprenaline

Q: Which of the following drugs is an irritant purgative
Liquid paraffin
Castor oil
Magnesium sulphate
Bisacodyl

Q: Which of the following is a diuretic
Frusemide
Chlorothiazide
Spironolactone
All of above

Q: Methotrexate is a
Antimalignant
Anti-Malarial
Purgative
Antiseptic

Q: Amyl nitrate pearls are administered by
Oral route
Parenteral route
Sublingual
Inhalation

Q: Heparin is an anticoagulant given by
Induction
Parenteral route
sublingual route
None of above

Q: Which of the following drugs is similar to carbidopa in the pharmacological category
Levodopa
Amantadine
Benserazide
Bromocryptine

Q: What is the primary site of action for spironolactone and triamterene?
Descending tube of Henle
Ascending tube of Henle
Proximal tubules
Distal collecting tubule

Q: A local anesthetic agent is
Ether
Nitrous oxide
Cyclopropane
Procaine HCl

Q: Most of the drugs will bind with which of the following plasma proteins?
Globulin
Albumin
Histone
Glycoprotein

Q: Fluoroquinolones are excellent agents for
UTI infections
Malaria
Amoebiasis
Typhoid

Q: An agent commonly combined with local anesthetics is
Ephedrine
Isoproterenol
Phenylephrine
Epinephrine (Adrenaline)

Q: Diuretic does
Cause vomitings
Cause water retention
Increase the outflow of urine
Decrease the outflow of urine

Q: Ammonium chloride is used as
diuretic
Expectorant
Systemic acidifier
all of above

Q: Pamidronate is used in
Mdnneir’s disease
Pegat’s disease
Hodkin’s disease
Cushing’s disease

Q: An example of a sympathomimetic drug is
Adrenaline
Quinine
Atropine
reserpine

Q: Parathyroid gland secretes
Thyroxine
Parathormone
Adrenaline
Oxytocin

Q: Dapsone is used in the treatment of
Fungal disease
Leprosy
Headache
Fever

Q: Gardenal and luminal are brand names of
Butobarbitone
Phenobarbitone
Cyclobarbitone
all of above

Q: Simvastatin is used in
Hypertension
Congestive cardiac failure
Atherosclerosis
Myocardial infarction

Q: Phenytoin is a derivative of
Hydantoin
Oxazole
Isoxazole
tetrazole

Q: highly polar drugs are
Water insoluble
Water soluble
Slightly water soluble
Insoluble in water

Q: A drug used in scabies
Benzyl benzoate
Betamethasone
Chloroxylenol
None of these

Q: A non-barbiturate I.V anesthetic is
Thiopentone
Methohexitone
Propanidid
Phenobarbitone

Q: Ethosuximide is used as an
Anticonvulsant
Antitubercular
Antimalarial
Emetic

Q: Choose the non-systemic antacid amount of the following
Aluminium hydroxide
Magnesium trisilicate
Magnesium hydroxide
all of above

Q: A miotic drug used in glaucoma is
Chloroquine
Ephedrine
Pilocarpine
Amphetamine

Q: Famotidine is a
Antacid
digestant
Antibiotic
Mineral

Q: Solapsone is
diuretic
Anti-histamine
Used as leprosy
All of the above

Q: Excretion of volatile general anesthetics occur
Kidney
Lungs
Heart
Intestine

Q: Alcohol hallucinosis is commonly treated…
Barbiturates
Phenothiazines
Disulfiram
Caffeine

Q: Roxatidine is used to treat
Ulcer
Edema
Hypertension
C.C.F

Q: General anesthetic is
Thiopentone sodium
Phenobarbitone Injection
Procaine
Lignocaine

Q: The route of administration of bacitracin is
I.M
I.V
Oral
Topical

Q: Gentamycin is commonly used in combination with
Ampicillin
Oxacillin
Carbenicillin
None of above

Q: Insulin is usually given to diabetic patients by which route
Oral
I.V
Intraspinal
Subcutaneous

Q: A direct smooth relaxant used in hypertension is
Papaverine
Reserpine
Physostigmine
Theophylline

Q: The drugs belong to hallucinogens is
Emetine
Atropine
L.S.D
D.D.S

Q: Local hormones are
Antiemetics
Anti-convulsants
Autacoids
Analeptics

Anticancer Drugs MCQs | Clinical Pharmacy MCQs with answers |gpat pharmacology MCQ

Q: Anticancer drug is
Busulfan
Rifamycin
I.N.H
Atropine

Q: Antibiotics with antitumor activity used in cancer is
Mitomycin
Kanamycin
Gentamicin
Norfloxacin

Q: IN.H is used in the treatment of
T.B
Leprosy
AMoebiasis
Cancer

Q: Picrotoxin causes
Sedation
Convulsion
Analgesia
All of above

Q: The drug used in the treatment of malaria is
Amantadine
Chloroquine
Tolbutamide
Sorbitrate

Q: A toxic effect of alcohol is
Mitosis
Mydriasis
Respiratory depression
CNS stimulation

Q: An alkaloid used to treat meant of bronchial asthma is
Physostigmine
Reserpine
ephedrine
Atropine

Q: Amphetamine is an
Analeptic
Antiseptic
Astringent
All of above

Q: Amphetamine is an…
Antiseptic
Analeptic
Astringent
All the above

Q: Diazoxide (hyper stat) is administered
Orally
Intramuscular
I.V infusion
Rapid I.V injection

Q: Most of the local anesthetics are…
Ester of p-aminobenzoic acid
Amides of naphthoic acid
Allantoin derivatives
Esters of propionic acid

Q: Potent loop-diuretic is
Frusemide
mannitol
Esidrex
Urea

Q: Drug useful in Zollinger-Ellison syndrome is
Ranitidine
Cimetidine
Sucralfate
Omeprazole

Q: Teratogenic malformation is
Photophobia
Phocomelia
Phagocytosis
None

Q: A skeletal muscle relaxant is
Tubocurarine
Propranolol
Adrenaline
Chloroquine

Q: Proton pump inhibitor is
Sucralfate
Milk of magnesia
Ranitidine
Omeprazole

Q: One of the drugs used in eye infections is
Sulfadiazine
Sulfacetamide sodium
Sulphadoxine
Sulphaguanidine

Q: The interaction of tetracycline with metal ions is an example of
Protein displacement
Antagonistic effect
Complexation and absorption
Alteration of GI absorption

Q: Drug combination warfarin/vitamin K results in specific interactions that identify
Increase sedation
No known interactions
Antagonistic
Harmful only in the presence of oxidizing agents

Q: A drug used as a nasal decongestant
Xylometazoline
Morphine
Pilocarpine
Atropine

Q: Propylthiouracil is an example of
Male sex hormone
Antithyroid drugs
Antimalarials drugs
Female sex hormones

Q: One of the drugs when co-administrated with terfenadine may lead to life-threatening cardiac dysrhythmias identify
Lomefloxacin
Clofazimine
Itraconazole
Neomycin

Q: Carminatives are drugs used to
To remove the gas from the stomach
to decrease secretions from the lungs
To increase bile secretions
For pre-anesthetic medication

Q: Antibiotic which interacts with calcium ions is
Erythromycin
Tetracycline
Streptomycin
Ampicillin

Q: The anticancer antibiotic is
Chloramphenicol
Bleomycin
Ciprofloxacin
Gentamycin

Q: In supraventricular arrhythmia digoxin when supplemented with …is dangerous
Quinidine
Procaine
Calcium
Xylocaine

Q: A person taking nitroglycerin consumes alcohol the drug interactions with alcohol and the effect seen is
Severe hypotension and collapse
Drowsiness
Anticoagulant effect
Hypertension

Q: One of the following drugs used in Parkinsonism is
Levodopa
Pethidine
Dimenhydrinate
Streptomycin
Pethidine

Q: Co-administration of NSAIDs with warfarin may often lead to
Antagonistic interactions
Interactions due to changes in the drug transport
Interactions due to disturbance in electrolyte balance
Additive or synergistic interactions

Q: Antiviral drug is
Metronidazole
Chloroquine
Interferon
Quinine

Q: A 45-year-old patient developed severe thrombocytopenia due to unfractionated heparin so the best alternative anti-coagulant will be:
Abciximab
Urokinase
Lepirudin
Plasminogen

Q: An example of a volatile liquid general anesthetic is…
Nitrous oxide
Ether
Cyclopropane
Propanidid

Q: Antifungal antibiotics used orally
Kanamycin
Griseofulvin
Chlortetracycline
None of above

Q: A 30-year-old male suffering from cerebral edema will be best treated with:
Amiloride
Furosemide
Ethacrynic acid
Mannitol

Q: An example of a local anesthetic drug is
Cyclopropane
Cocaine HCl
Nitrous oxide
Ether

Q: A drug is reported to have a biological half-life of 2 hours. At the end of 8 hours what percentage of the drug,s will the original activity remain?
2.5%
12.5%
25%
6.25%

Q: Drugs used in mania orally
Reserpine
Chlorpromazine
Lithium carbonate
Haloperidol

Q: A 35-year-old patient complaining of severe pain along the right side of the jaw and face; the best choice for this neuralgic pain is:
Ibuprofen
Methadone
Carbamazepine
None

Q: Anti-rheumatic drug is
Digitalis
Chloroquine
Aspirin
Atropine

Q: While prescribing a treatment to a young female patient suffering from peptic ulcer associated with H. pylori the gastroenterologist will neglect:
Vancomycin
Tetracycline
Amoxicillin
Metronidazole

Q: Poisoning caused by organophosphate compounds is treated with
Pethidine
Charcoal
Pralidoxime
Caffeine

Q: Apomorphine is used as a
Purgative
Ecbolic
Emetic
Diuretic

Q: Cycloserine is analog of
D-Alanine
D-Serine
L-Serine
L-Alanine

Q: Nitroglycerin is used in…
Leprosy
General anesthetic
Local anesthetic
Angina Pectoris

Q: Nikethamide is a
Respiratory stimulant
Purgative
Muscle relaxant
Hypnotic

Q: Succinylcholine chloride is an
Hypnotic
Diuretic
Muscle relaxant
Antibiotic

Q: Hydrogen peroxide is a
Hypertensive drug
Antiseptic
Mydriatic
Helminthic

Q: Phenobarbitol is classified as a
Short-acting barbiturate
Long-acting barbiturate
Intermediate-acting barbiturate
Ultra short-acting barbiturate

Q: Barbiturates are
Derived from malonic acid
Cyclic ureides
Urea derivatives
All of the above

Q: Toxic metabolite of paracetamol
N-acetyl p-benzoquinone imine
N-acetyl p-benzoquinone amine
O-dialkyl acetaminophen
None of above

Q: Which of the following drugs is a prodrug?
Nimesulide
Indomethacin
Diclofenac
Nabumetone

Q: One of the following is a selective COX-2 inhibitor
Paracetamol
Nimesulide
Valdecoxib
None

Q: Anaemia is treated with
Chloroquine
Hetrazan DES
Ferrous sulphate
Metronidazole

Q: Sulfide metabolites of one of the following are active
Ketoprofen
Naproxen
Piroxicam
Sulindac

Q: Amiodarone has ……. basic nucleus
Benzothiazole
Benzophenone
Benzofuran
Benzopyrrole

Q: Progesterone is a
Male hormones
Pancreatic enzyme
Female hormone
Salivary juice

Q: An example of a beta receptor blocker
Lobeline
Cocaine
Atenolol
Ergotamine

Q: The drug used in bronchial asthma is
Sodium chloride
Insulin
Vitamin-E
Salbutamol

Q: Ethacrynic acid is used primarily as a
Diuretic
Antiemetic
Laxative
Sedative

Q: A most serious side effect of spironolactone is
Hyperkalemia
Hypokalemia
Hypernatremia
Hyponatremia

Q: The angiotensin receptor antagonist used in hypertension
Enalapril
Captopril
Losartan
Nifedipine

Q: Which of the following is not short-acting insulin preparation?
Insulin lispro
Insulin Aspart
Glargine insulin
None

KD Tripathi pharmacology book MCQ | MCQs in pharmacology with explanatory answers pdf

Q: Which of the following diuretics is similar to that of diazoxide?
Acetazolamide
Furosemide
Mannitol
Chlorothiazide

Q: Serotonin antagonist is
Tolbutamide
Glutethimide
Caffeine
Methysergide

Q: Which of the following is not an endogenous opioid peptide?
Met-enkephalin
Leu enkephalin
Dynorphin
Beta lipotropin

Q: A toxic effect of alcohol is
Respiratory depression
Mydriasis
Miosis
CNS stimulant

Q: Distribution is perfusion rate limited in case of ……..drugs
Ionic
Lipophilic
Polar
Water soluble

Q: long term use of thiazide diuretic in hypertension can produce all of the following except
Hyperkalemia
Hyperuricemia
Hyperlipidemia
Hyperglycemia

Q: The active metabolite of primidone responsible for the antiepileptic activity is:
Phenytoin
Gabapentin
Phenobarbitone
Diazepam

Q: Spironolactone acts by antagonizing
Insulin
Glucagon
Aldosterone
Histamine

Q: Which one of the calcium channel blockers used as anti-anginal agents has the highest possibility to produce a negative inotropic effect, AV nodal block, bradycardia, decrease cardiac output, constipation, edema, and is contraindicated in sick sinus syndrome
Amlodipine
Nifedipine
Diltiazem
Verapamil

Q: Protriptyline is used mainly as an
Antispasmodic
Antidepressant
Analgesic
Antiemetic

Q: Conversion of T4 to T3 inhibition is associated with…
Propylthiouracil
Radioactive iodine
Lugol’s iodine
Carbimazole

Q: Vigabatrin produces anti-epileptic activity through…
A) Potentiating GABA-mediated neuronal inhibition by depressing GABA transporters
B) Modifying synaptic release of glutamate/GABA by binding to a specific synaptic protein
C) Inhibiting GABA transaminase enzyme which degrades GABA
D) Potentiating postsynaptic GABA receptor effect

Q: The drug of choice for trigeminal neuralgia is
Phenytoin
Diazepam
Trimethadione
Carbamazepine

Q: Antidote for curare poison is
Atropine
Neostigmine
Homatropine
Hexamethonium

Q: the immunosuppressant action of cyclosporine is due to
interference with antigen recognition
inhibition of gene transcription of interleukins
Blockage of tissue response to inflammatory
inhibition of cell wall synthesis

Q: Aminophylline is used most frequently in
Nephrotic edema
Diabetes insipidus
Asthma
Lowering cerebral pressure

Q: A 3-year-old child presented to OPD with the symptoms of influenza aspirin is contraindicated in the patient because of the increased risk of
Gastric bleeding
Thrombocytopenia
Fanconi syndrome
Reye’s syndrome

Q: Bacillary dysentery is usually caused by
E. coli
Shigella
Pasteurella
Non of above

Q: Which of the following is a wrongly matched combination of antiarrhythmic drugs and their class
Lidocaine-IB
Disopyramide-II
Diltiazem-IV
Amiodarone-III

Q: Acyclovir (Zovirax) is classified as
Anthelmintic
Antiemetic
Antacid
Anti-viral

Q: Which of the following drug combinations are not synergistic in nature?
Amoxicillin+clavulanic acid
Nitrofurantoin+Nalidixic acid
Pyrimethamine+sulfadoxine
Sulfamethoxazole+ Trimethoprim

Q: Drugs used to treat ringworm in the body is
Iodoform
Boric acid
Gentamycin
Tolnaftate

Q: Does Tachyphylaxis refer to which of the following?
a) Responsiveness increased rapidly after the administration of a drug
b) Responsiveness decreases rapidly after the administration of a drug
c) Responsiveness increased rapidly after the maintenance of a drug (hypersensitive)
d) Responsiveness decreases rapidly after the maintenance of a drug (desensitized)

Q: The drug commonly used to prevent sepsis in severe bum cases is
Sulfadiazine sodium
Sulfamethoxazole+ Trtimethoprime
Salazopyrin
Sulphadimidine

Q: A hypertensive patient Mr. X already received the drug ‘X’ to control his blood pressure and was prescribed a tricyclic antidepressant. this resulted in the abolition of the antihypertensive action of ‘X’. Which of the following drugs could be ‘X’?
Enalapril
Clonidine
Atenolol
Diltiazem

Q: Cephalosporins are
Antigens
Antibiotic
Serums
Vaccines

Q: Which of the following orally active testosterone derivatives has progestational activity?
Oxymesterone
Dihydrotestosterone
Ethisterone
Nomegestrol

Q: Tricyclic antidepressant used in severe depression is
Doxepin
Emetine
Diazepam
None of these

Q: Which of the following drugs belong to a class of antibiotics called ansamycins
Rifampin
Streptomycin
Azithromycin
Streptozotocin

Q: Which amount of the following statement is correct with respect to their mechanism of action
Sitagliptin/Vildagliptin: Dipeptidyl peptidase-4 inhibitors
Dapagliflozin/canagliflozin: AMPk activator
Glibenclamide/Glimepiride: Alpha glucosidase inhibitors
Acarbose/Metformin: KATP channel blockers

Q: Clomipramine exerts potent
Antiemetic action
Antitussive effect
Astringent
Antidepressant action

Q: The most common side effect of nitroglycerine is
Diarrhea
Hypertension
Sedation
Headache

Q: Thiazides are used as
Sedatives
Diuretic
Anticonvulsant
All of above

Q: Which of the following is a female sex hormone?
Stilbesterol
Testosterone
Estrogen
Benzesterol

Q: Chloroquine is a
4-Amino quinoline
Acridine
Biguanide
Pyrimidine

Q: Mannitol is used as a
Loop diuretic
Osmotic diuretic
Potassium-sparing diuretic
Carbonic anhydrase diuretic

Q: Dipyridamole is used primarily for
Angina pectoris
Atherosclerosis
Myocardial infarction
Mon of these

Q: A parenteral anticoagulant drug is
Penicillin
Phenindione
Warfarin
Heparin

Q: Mianserin is used as an
Antiemetic
Antipsychotic
Antidepressant
All of these

Q: Vitamin B12 and folic acid are used in the treatment of
Megaloblastic anemia
Anaemia
Sickle cell anemia
Aplastic anemia

Q: Which of the following is not a benzodiazepine?
Diazepam
Nitrazepam
Zolpidem
Triazolam

Q: Oral iron preparation is used as haematinic is
Ferrois salphate
Ferrous gluconate
Ferrous fumarate
All of above

Q: A chelating agent used in the case of poisoning is
Sodium phosphate
Dimercaprol
Ferroin
Bismuth subnitrate

MCQs in pharmacology that asked repeatably

Q: A specific antidote for warfarin sodium is
Protamine
Menadione
Vitamine K1
None of above

Q: The oral hypoglycemic agent is
Tolbutamide
Glipizide
Chlorpropamide
All of these

Q: Leukotriene receptor antagonist used in allergic cough is
Rofecoxib
Theophylline
Losartan
Montelukast

Q: The constituent of cholesterol termed bad cholesterol
HDL
LDL
VLDL
Triglycerides

Q: Which of the following is an antifungal antibiotic
Naftifine”
5-Flucytosine
Nystatin
Nafimidone

Related: Top Industrial Pharmacy MCQs

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References:

KD Tripathi pharmacology book

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